Oligoclonal immunoglobulins and multiple sclerosis.

Oligoclonal immunoglobulins and plasma cells in spinal fluid of patients with multiple sclerosis.

A new modification of polyacrylamide gel electrophoresis (PAGE) was applied to cerebrospinal fluid proteins from patients with multiple sclerosis (MS). The same spinal fluids were also examined by a cytological technique. Over 90% of patients with clinically definite or early probable or latent MS showed abnormal PAGE patterns in the form of oligoclonal gammaglobulin bands. Reactive (atypical, ...

CSF -- oligoclonal bands in multiple sclerosis.

The present paper is concerned with a correlation between clinical parameters of multiple sclerosis and different agar gel electrophoretical patterns in CSF. The agar gel electrophoresis represents clearly the most sensitive method for the demonstration of oligoclonal bands in CSF.

Reibergram and oligoclonal bands in diagnosis of multiple sclerosis.

INTRODUCTION In this study authors have analyzed the correlation between the IgG immunoglobulins in cerebrospinal fluid and the findings of oligoclonal bands on gel. Immunoglobulin IgG in cerebrospinal fluid (CSF) can be detected in neurological diseasses (infections and inflammatory neurological diseases and in demyelinating diseases, like multiple sclerosis (MS)). Quantitative IgG in CSF can ...

More on oligoclonal bands and diagnosis of multiple sclerosis.

A When we consider that creatinine and uric acid, for example, are excreted in concentrations of about 15 and 5 mmoLfL, we can already observe positive biases caused by these interferencesat a sample:reagent volume ratio of 1:5 (1). However, this ratio does not yet permit measurement of microalbuminuria. Thus, the interferingreactions of urinary components with bromphenol blue preclude use of t...

Oligoclonal immunoglobulins in HIV-antibody-positive serum.